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Circadian Peptide

DSIP

Delta-Sleep PeptideEmideltide

A 9-amino acid peptide that modulates delta-wave sleep architecture and circadian rhythm signaling, studied for sleep onset mechanisms in laboratory models. Premium Direct-Supply Peptide.

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Verified Test Results

Every batch, independently verified.

Each batch is analyzed by an ISO/IEC 17025 accredited third-party laboratory. The report below reflects the identity, purity and full-panel specification data reported by the lab.

ILSILS LaboratoriesCertificate of Analysis≥99%Purity by HPLC
ISO 17025 Accredited8× Tested
ParameterResultMethodSpecification
Peptide Purity (HPLC)99.45%HPLC>= 95%
Net Peptide Content5.22mgHPLCReport
Identity (HPLC)ConfirmedHPLCMeets spec
AppearanceGoodVisualMeets spec
Fentanyl ScreenNot DetectedImmunoassayPass
Heavy Metals (ICP-MS)Not DetectedICP-MSPass
Sterility (PCR)No GrowthPCRPass
Endotoxin (USP <85>)0.107 EU/mLUSP <85>Reported

Third-Party Verified

Certificate of Analysis

Every lot is HPLC-tested at an ISO/IEC 17025-accredited lab. Open any batch's certificate below.

COA information

DSIP 5mg

Latest

LOT DSP0001

99.45%HPLC purity · meets spec
Labeled
5mg
Measured
5.22mg
Identity
Confirmed
Heavy metals
Not Detected
Sterility
No Growth
Endotoxin
0.107 EU/mL
Tested
Jul 30, 2026

8 assays passed · ISO/IEC 17025 accredited

Certificate of AnalysisDSIP 5mg · LOT DSP0001
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Compound Information

Technical specifications

MOLECULAR PROFILE

What Is DSIP?

Naturally occurring nonapeptide first isolated from rabbit brain in 1977

NonapeptideEndogenous
Type
Synthetic nonapeptide
CAS Number
62568-57-4
Molecular Formula
C35H48N10O15
Molecular Weight
848.8 g/mol
Amino Acids
9 residues
Sequence
Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu

STORAGE REQUIREMENTS

Stability Information

Handle with care to maintain potencyLight sensitiveTemperature sensitive

Lyophilized (powder)-20°Cprotect from light

Reconstituted2-8°C

Stability15 minutes (plasma half-life)

product status

Development History

First isolated from rabbit brain in 1977 by Schoenenberger & Monnier

Discovery1977, SwitzerlandDiscoverersSchoenenberger & MonnierOriginRabbit mesodiencephalic ventricleINN NameEmideltideHuman Studies1980s-presentRegulatory Statuspremium productsOriginal discovery

Product Guides & References

Verified publications and source documentation

EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Delta sleep-inducing peptide

2001Pollard BJ, Pomfrett CJD
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INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY, THERAPY, AND TOXICOLOGY

Acute and delayed effects of DSIP on human sleep behavior

1981PMID: 6895513Schneider-Helmert D, et al.
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NEUROPSYCHOBIOLOGY

Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients

1992DOI: 10.1159/000118919PMID: 1299794Bes F, Hofman W, Schuur J, Van Boxtel C
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EUROPEAN NEUROLOGY

DSIP in the treatment of withdrawal syndromes from alcohol and opiates

1984DOI: 10.1159/000115715PMID: 6548969Dick P, Costa C, Fayolle K, et al.
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EUROPEAN NEUROLOGY

Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes

1984DOI: 10.1159/000115716PMID: 6548970Larbig W, Gerber WD, Kluck M, Schoenenberger GA
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NEUROPSYCHOBIOLOGY

Effects of DSIP in man: Multifunctional psychophysiological properties besides induction of natural sleep

1983PMID: 6689058Schneider-Helmert D, Schoenenberger GA
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INTERNATIONAL JOURNAL OF NEUROSCIENCE

DSIP—a tool for investigating the sleep onset mechanism: a review

1988DOI: 10.3109/00207458808990695PMID: 3286557Yehuda S, Carasso RL
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MOLECULES

Delta Sleep-Inducing Peptide Recovers Motor Function in SD Rats after Focal Stroke

2021DOI: 10.3390/molecules26175173PMID: 34500605Tukhovskaya EA, et al.
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PUBCHEM DATABASE

Delta Sleep-Inducing Peptide

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