Semax 10mg
LatestLOT SMX0002
99.93%HPLC purity · meets spec
- Labeled
- 10mg
- Measured
- 10.61mg
- Identity
- Confirmed
- Heavy metals
- Not Detected
- Sterility
- No Growth
- Endotoxin
- < 0.05 EU/mL
- Tested
- Jul 30, 2026
8 assays passed · ISO/IEC 17025 accredited
Cognitive & Neuroprotective Peptide
SEMAX
ACTH (4-10)ACTH (4-7)-Pro-Gly-ProMet-Glu-His-Phe-Pro-Gly-ProMEHFPGPCAS: 80714-61-0
A 7-amino acid synthetic heptapeptide analog of ACTH (4-10) that upregulates BDNF expression and modulates the TrkB signaling pathway, studied for cognitive enhancement and neuroprotection in clinical studies. Premium Direct-Supply Peptide.
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Quantity
From$64
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Verified Test Results
Every batch, independently verified.
Each batch is analyzed by an ISO/IEC 17025 accredited third-party laboratory. The report below reflects the identity, purity and full-panel specification data reported by the lab.
ILSILS LaboratoriesCertificate of Analysis≥99%Purity by HPLC
ISO 17025 Accredited8× Tested
ParameterResultMethodSpecification
Peptide Purity (HPLC)99.93%HPLC>= 95%
Net Peptide Content10.61mgHPLCReport
Identity (HPLC)ConfirmedHPLCMeets spec
AppearanceGoodVisualMeets spec
Fentanyl ScreenNot DetectedImmunoassayPass
Heavy Metals (ICP-MS)Not DetectedICP-MSPass
Sterility (PCR)No GrowthPCRPass
Endotoxin (USP <85>)< 0.05 EU/mLUSP <85>Reported
Third-Party Verified
Certificate of Analysis
Every lot is HPLC-tested at an ISO/IEC 17025-accredited lab. Open any batch's certificate below.
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Compound Information
Technical specifications
MOLECULAR PROFILE
What Is Semax?
Synthetic heptapeptide analog of ACTH (4-10) with C-terminal Pro-Gly-Pro extension for enhanced stability
HeptapeptideACTH Analog
- Type
- Synthetic heptapeptide
- CAS Number
- 80714-61-0
- Molecular Formula
- C37H51N9O10S
- Molecular Weight
- 813.9 g/mol
- Amino Acids
- 7 residues
- Sequence
- Met-Glu-His-Phe-Pro-Gly-Pro
STORAGE REQUIREMENTS
Stability Information
Handle with care to maintain potencyLight sensitiveTemperature sensitive
Lyophilized (powder)-20°Cprotect from light
Reconstituted2-8°C
Nasal spray2-8°C30 days after opening
DEVELOPMENT STATUS
Regulatory Information
Developed at the Institute of Molecular Genetics of the Russian Academy of Sciences
- Developer
- Russian Academy of Sciences
- Approval
- Russia (1990s)
- Indications
- Stroke, cognitive impairment
- Formulations
- 0.1% and 1% nasal spray
- US Status
- Not FDA-approved
- Related Peptide
- Selank (tuftsin analog)
Product Guides & References
Verified publications and source documentation
BRAIN product
Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus
2006•DOI: 10.1016/j.brainres.2006.07.108•PMID: 16996037Dolotov OV, Karpenko EA, Inozemtseva LS, et al.
View Source BMC GENOMICSThe peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia
2014•DOI: 10.1186/1471-2164-15-228•PMID: 24661656Medvedeva EV, Dmitrieva VG, Povarova OV, et al.
View Source ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S.S. KORSAKOVAThe efficacy of semax in the treatment of patients at different stages of ischemic stroke
2018•PMID: 29798983
View Source JOURNAL OF MOLECULAR NEUROSCIENCEComparison of the temporary dynamics of NGF and BDNF gene expression in rat hippocampus, frontal cortex, and retina under Semax action
2010•DOI: 10.1007/s12031-009-9270-z•PMID: 19662538Shadrina M, Kolomin T, Agapova T, et al.
View Source INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESNovel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Molecular Level
2020•PMID: 32575851
View Source ALZHEIMER'S DRUG DISCOVERY FOUNDATION
