5-Amino-1MQ 50mg
LatestLOT AMQ0002
99.97%HPLC purity · meets spec
- Labeled
- 50mg
- Measured
- 51.64mg
- Identity
- Confirmed
- Heavy metals
- Not Detected
- Sterility
- No Growth
- Endotoxin
- < 0.05 EU/mL
- Tested
- Jul 30, 2026
8 assays passed · ISO/IEC 17025 accredited
Metabolic Peptide
5-Amino-1MQ
5-Amino-1-Methylquinolinium5A1MQNNMTiCAS: 42464-96-0
A selective small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) that modulates NAD+ salvage and lipogenesis pathways in preclinical metabolic laboratory models. Premium Direct-Supply Peptide.
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From$179
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Verified Test Results
Every batch, independently verified.
Each batch is analyzed by an ISO/IEC 17025 accredited third-party laboratory. The report below reflects the identity, purity and full-panel specification data reported by the lab.
ILSILS LaboratoriesCertificate of Analysis≥99%Purity by HPLC
ISO 17025 Accredited8× Tested
ParameterResultMethodSpecification
Peptide Purity (HPLC)99.97%HPLC>= 95%
Net Peptide Content51.64mgHPLCReport
Identity (HPLC)ConfirmedHPLCMeets spec
AppearanceGoodVisualMeets spec
Fentanyl ScreenNot DetectedImmunoassayPass
Heavy Metals (ICP-MS)Not DetectedICP-MSPass
Sterility (PCR)No GrowthPCRPass
Endotoxin (USP <85>)< 0.05 EU/mLUSP <85>Reported
Third-Party Verified
Certificate of Analysis
Every lot is HPLC-tested at an ISO/IEC 17025-accredited lab. Open any batch's certificate below.
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Compound Information
Technical specifications
MOLECULAR PROFILE
What Is 5-Amino-1MQ?
- Type
- Small molecule NNMT inhibitor
- CAS Number
- 42464-96-0
- Molecular Weight
- 159.21 g/mol (cation)
- Salt Form
- 286.11 g/mol (iodide salt)
- Formula
- C₁₀H₁₁N₂⁺ (cation)
- Appearance
- Brown to reddish-brown solid
STORAGE REQUIREMENTS
Stability Information
Soluble in DMSOAvoid repeated freeze-thawAliquot after reconstitution
Lyophilized (powder)-20°Cstable 24+ months
Short-term storage2-8°Cup to 30 days
Reconstituted2-8°C
Product Guides & References
Verified publications and source documentation
JOURNAL OF MEDICINAL CHEMISTRY
Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase
2017•DOI: 10.1021/acs.jmedchem.7b00389•PMID: 28548833Neelakantan H, Wang HY, Vance V et al.
View Source BIOCHEMICAL PHARMACOLOGYSelective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
2018•DOI: 10.1016/j.bcp.2017.11.007•PMID: 29155147Neelakantan H, Vance V, Wetzel MD et al.
View Source BIOCHEMICAL PHARMACOLOGYSmall molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle
2019•DOI: 10.1016/j.bcp.2019.02.008•PMID: 30753815Neelakantan H, Brightwell CR, Graber TG et al.
View Source SCIENTIFIC REPORTSCombined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice
2021•DOI: 10.1038/s41598-021-85051-6•PMID: 33707534Sampson CM, Dimet AL, Neelakantan H et al.
View Source JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSISDevelopment & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies
2021•DOI: 10.1016/j.jpba.2021.114255•PMID: 34304009Awosemo O, Neelakantan H, Watowich S et al.
View Source JOURNAL OF OBSTETRICS AND GYNAECOLOGYSmall molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells
2021•DOI: 10.1080/01443615.2020.1854696•PMID: 33645410Akar S, Duran T, Azzawri AA et al.
View Source SCIENTIFIC REPORTSReduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
2022•DOI: 10.1038/s41598-021-03670-5•PMID: 35013352Dimet-Wiley A, Wu Q, Wiley JT et al.
View Source DIABETES, OBESITY AND METABOLISMNicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction
2024•DOI: 10.1111/dom.15879•PMID: 39161060Babula JJ, Bui D, Stevenson HL et al.
View Source 
